Important Home Pages

European Molecular Biology Laboratory (EMBL) http://www2.ebi.ac.uk/Help/General/general.html Cambridge, UK.

UK Human Genome Mapping Project - Resource Center (HGMP-RC) http://www.hgmp.mrc.ac.uk/

SeqNet: UK Node of European Molecular Biology Network (EMBNet) http://www.seqnet.dl.ac.uk/About/SEQNET/

GenBank http://www.ncbi.nlm.nih.gov/Genbank/ GenBank at the National Center for Biotechnology (NCBI) of The National Library of Medicine (NLM) at The National Institutes for Health (NIH) campus, USA.

DNA Databank of Japan (DDBJ) http://www.ddbj.nig.ac.jp

Genome Sequence DataBase (GSDB) http://seqsim.ncgr.org/ The National Center for Genome Resources, Genome Sequence Database. The server is a supercomputer with genomic algorithm accelleration.

Online Mendelian Inheritance in Man (OMIM) http://www3.ncbi.nlm.nih.gov/Omim/ Database of human genes and their disorders, with textual information, images and references. Links to Entrez and MedLine.

 

European Drosophila Genome Project http://edgp.ebi.ac.uk/

The Institute for Genomic Research (TIGR) http://www.tigr.org/

The Sanger Centre http://www.sanger.ac.uk/

ExPASY (Swiss Institute of Bioinformatics) http://www.expasy.ch/ ExPASY is not the Swiss EMBnet node!

GenomeNet (Japan) http://www.genome.ad.jp/

Australian National Genomic Information Service (ANGIS) http://morgan.angis.su.oz.au

Bioinformatics and Biology Resources on the Internet http://aeiveos.wa.com/biology/index.html An excellent site, well worth a visit!

List of other Genome Sites

 http://www.hgmp.mrc.ac.uk/GenomeWeb/ List of other genome web sites. Concise and clearly presented.

Brunel University Online Teaching Programme http://www.brunel.ac.uk/depts/bl/project/front.htm

 

Protein Sequence Databases

    

Translated EMBL (TrEMBL) http://www.expasy.ch/sprot/sprot-top.html Database of all the protein coding regions stored in the EMBL database. Comprehensive, but (generally) at the cost of poor annotation.

SWISS-PROT http://expasy.hcuge.ch/sprot/sprot-top.html A database of protein sequences, translated from the EMBL genomic database. Protein sequences have been checked and annotated.

PIR http://www_nbrf.georgetown.edu/pir/ Four databases: PIR1 is the most comprehensive with entries classified and annotated. PIR4 is the least comprehensive, with un encoded

 

Motif Databases

    

Pratt Search (EMBL) 4-4-2-PU http://www2.ebi.ac.uk/pratt/ Interactively identifies conserved patterns from a series of user-entered unaligned protein sequences.

PROSITE (via EBI) http://www2.ebi.ac.uk/ppsearch/ Pattern search to identify conserved functional amino acid motifs. Scans a sequence against PROSITE (the primary motif database) with a graphical output.

PROSITE http://expasy.hcuge.ch/sprot/prosite.html The primary motif database. Take care! Motifs are often short, and a large number of false positives should be expected! Options are available to exclude those which most commonly lead to false results.

Protein Motif Fingerprints http://www.biochem.ucl.ac.uk/bsm/dbbrowser/PRINTS.html